منابع مشابه
Operator constitutive mutations in the leucine operon of Salmonella typhimurium.
N a previous communication (CALVO, FREUNDLICH and UMBARGER 1969), a I group of Salmonella typhimurium mutants was described as having the following properties. They were resistant to an analog of leucine, 5’,5’,5’-trifluoroDL-leucine (RENNERT and ANKER 1963), excreted leucine, had constitutive and derepressed levels of enzymes involved in leucine biosynthesis, and they had mutant sites linked t...
متن کاملConstitutive mutations of the Salmonella enterica serovar Typhimurium transcriptional virulence regulator phoP.
The PhoP-PhoQ two-component system is necessary for the virulence of Salmonella spp. and is responsible for regulating several modifications of the lipopolysaccharide (LPS). Mutagenesis of the transcriptional regulator phoP resulted in the identification of a mutant able to activate transcription of regulated genes approximately 100-fold in the absence of PhoQ. Sequence analysis showed two sing...
متن کاملSuppressors of recB mutations in Salmonella typhimurium.
Using a screen that directly assesses transductional proficiency, we have isolated suppressors of recB mutations in Salmonella typhimurium. The alleles of sbcB reported here are phenotypically distinct from those isolated in Escherichia coli in that they restore recombination proficiency (Rec+), resistance to ultraviolet light (UVR), and mitomycin C resistance (MCR) in the absence of an accompa...
متن کاملMutations affecting regulation of cobinamide biosynthesis in Salmonella typhimurium.
Transcription of the genes for cobalamin biosynthesis is reduced during aerobic growth. We isolated and characterized mutants that showed a 2- to 90-fold increase in aerobic expression of the cobinamide biosynthesis (CobI) genes, depending on the particular mutation and growth conditions. Four different classes of mutations were characterized. All mutations (CobRI through CobRIV) were cis-actin...
متن کاملNew suppressors of frameshift mutations in Salmonella typhimurium.
Several new types of suppressor mutants have been isolated. These were identified among revertants of mutants originally generated by mutagens other than the acridine-derived ICR191. The new suppressors correct mutations other than those with runs of C or G which are recognized by the previously described suppressors. Several frameshift mutations are corrected by more than one suppressor type. ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1989
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1989.tb03433.x